21 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... form part of the differential ... However, in UMN ... UMN lesions are ... and a positive Babinski
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
involving both UMN ... (3) primary lateral ... combination of UMN ... conditions listed in differential ... neurology #diagnosis #management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... LFTs #Elevated #Abnormal
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... Mild ALT < 5x ULN ... disease US — Normal ... #LiverEnzymes #Differential
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
→ Primary hyperapara ... likely - Mid range/ULN ... → Primary hyperpara ... • If all normal ... Hypercalcemia #workup #differential
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Diagnosis and Management ... Ascites PMN > ... SBP: Medical Management ... response - ↓ PMN ... ) prophylaxis Primary
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... injury • Gait is abnormal ... dysfunction • Abnormal ... : Areflexia UMN ... plantar response LMN
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
Diagnosis and Management ... : cell count + differential ... source • SBP: PMN ... count (WBC x PMN ... Ascites #Diagnosis #Management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
upper limit of normal ... Hepatitis (eg Viral) Management ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... AIH #Diagnosis #Management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... • ALT & AST normal ... • ALP > 1.5 x ULN ... bile ducts Differential ... malignancy #Primary