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diagnosis hepatology neurology treatment algorithm biliary cirrhosis nephrology pbc sclerosis workup aflp als amyotrophic atrophy calcium cholangitis cord disorders elevated
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
form part of the differential ... However, in UMN ... UMN lesions are ... This lesion causes ... and a positive Babinski
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... (3) primary lateral ... Escorial criteria uses ... conditions listed in differential ... neurology #diagnosis #management
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... #LiverEnzymes #Differential ... Diagnosis #Algorithm #Causes
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Evaluation 1) Clinical clues ... → Primary hyperapara ... likely - Mid range/ULN ... → Primary hyperpara ... Hypercalcemia #workup #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... injury • Gait is abnormal ... Non-compressive Spinal Cord Causes ... : Areflexia UMN ... plantar response LMN
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... intralobular bile ducts causes ... • ALP > 1.5 x ULN ... bile ducts Differential ... malignancy #Primary
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... AST/ALT (5-10x ULN ... infiltration) Differential ... Intrahepatic Cholestasis Management ... obgyn #diagnosis #management
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... Progressive MS • Primary ... sclerosis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Summary Causes ... Labs: • CPK 5X ULN ... #causes #treatment
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... if ALP > 1.5x ULN ... and/or abnormal ... disease #PBC #Primary
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