9 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... form part of the differential ... diagnosis. ... However, in UMN ... and a positive Babinski
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... involving both UMN ... - Causes progressive ... Escorial criteria uses ... conditions listed in differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... disease US — Normal ... #Diagnosis #Algorithm ... #Causes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... LFTs #Elevated #Abnormal ... #diagnosis #hepatology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... Diagnosis Framework ... Non-compressive Spinal Cord Causes ... : Areflexia UMN ... #algorithm
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Evaluation 1) Clinical clues ... likely - Mid range/ULN ... • If all normal ... Hypercalcemia #workup #differential ... #diagnosis #endocrinology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... AST/ALT (5-10x ULN ... infiltration) Differential ... Diagnosis: Viral
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... • ALP > 1.5 x ULN ... bile ducts Differential ... Diagnosis: •
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Idiopathic • Normal ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm