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diagnosis hepatology neurology algorithm workup aflp als amyotrophic atrophy biliary calcium childhood cholangitis cirrhosis cord disorders elevated endocrinology evaluation fatty
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... form part of the differential ... However, in UMN ... This lesion causes ... and a positive Babinski
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... conditions listed in differential ... neurology #diagnosis #management
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... #LiverEnzymes #Differential ... Diagnosis #Algorithm #Causes
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... injury • Gait is abnormal ... Non-compressive Spinal Cord Causes ... : Areflexia UMN ... plantar response LMN
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... AST/ALT (5-10x ULN ... infiltration) Differential ... #pathophysiology
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Evaluation 1) Clinical clues ... likely - Mid range/ULN ... FeCa <1 %) - Low normal ... • If all normal ... Hypercalcemia #workup #differential
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... within CNS causing MN ... genital warts, abnormal ... peds #pediatrics #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... • ALT & AST normal ... • ALP > 1.5 x ULN ... bile ducts Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Summary Causes ... Labs: • CPK 5X ULN ... #causes #treatment
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Sjogren's • CSF: - Abnormal ... • Infectious causes ... Myelitis #diagnosis #management ... #neurology #differential
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