15 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
form part of the differential ... However, in UMN ... UMN lesions are ... and a positive Babinski ... @DharSaty #UMN
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of UMN ... sclerosis with pure UMN ... combination of UMN ... conditions listed in differential ... diagnosis column Treatment
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis
Spontaneous Bacterial Peritonitis
 • Cirrhosis (high SAAG)
) + ascites w/ PMN ... > 250 • Treatment ... glucose < 50, LDH ULN ... Positive Culture • Treatment ... Peritoneal #diagnosis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... Mild ALT < 5x ULN ... disease US — Normal ... #LiverEnzymes #Differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... injury • Gait is abnormal ... dysfunction • Abnormal ... : Areflexia UMN ... plantar response LMN
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
likely - Mid range/ULN ... FeCa <1 %) - Low normal ... • If all normal ... Hypercalcemia #workup #differential
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
upper limit of normal ... ALT + AST > 10x ULN ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... regarding need for treatment
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... (>10^6 IU/mL), normal ... (<2000 IU/mL), normal ... (>10^6 IU/mL), normal ... IU/mL and ALT > ULN
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... of ALP • Near normal ... chemistry #diagnosis #differential