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diagnosis hepatology algorithm lfts transaminitis workup amyotrophic autoimmune biliary calcium causes chemistry cholangitis cirrhosis cord disorders endocrinology evaluation hypercalcemia interpretation
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
muscles, muscle atrophy ... progressive muscular atrophy ... loss of muscle (atrophy ... conditions listed in differential ... Lateral #Sclerosis #neurology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... >15X ULN ... < 5x ULN ... kwburak #LFTs #Elevated
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... > 15x ULN • Viral ... disease US — Normal ... #LiverEnzymes #Differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
/ULN ALT) / (Alk ... phos/ULN ALP) ... specificity to elevated ... • Near normal ... chemistry #diagnosis #differential
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
likely - Mid range/ULN ... Vit D • If all ... normal, move on ... Hypercalcemia #workup #differential ... endocrinology #calcium #elevated
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... : Areflexia UMN ... Loss of muscle (atrophy ... disorders #diagnosis #neurology ... #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
& AST normal or ... slightly elevated ... early on but elevated ... > 1.5 x ULN • ... bile ducts Differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Antisynthetase syndrome (also ... Polymyositis or ALS ... kinase levels are elevated ... #rheumatology #differential
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