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diagnosis hepatology algorithm lfts rheumatology transaminitis workup autoimmune biliary calcium cardiology causes chemistry cholangitis cirrhosis cord endocrinology erythematosus evaluation flaccid
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
pathology and muscle disorders ... disorder and form ... part of the differential ... However, in UMN ... and a positive Babinski
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... kwburak #LFTs #Elevated
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... #LiverEnzymes #Differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... injury • Gait is abnormal ... : Areflexia UMN ... Loss of muscle (atrophy
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
likely - Mid range/ULN ... FeCa <1 %) - Low normal ... • If all normal ... Hypercalcemia #workup #differential ... endocrinology #calcium #elevated
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... specificity to elevated ... - If both are normal ... chemistry #diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
• ALT & AST normal ... or slightly elevated ... early on but elevated ... • ALP > 1.5 x ULN ... bile ducts Differential
Hypertensive Disorders of Pregnancy Chronic Hypertension: • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg •
Hypertensive Disorders ... liver enzymes (2x ULN ... of hemolysis, elevated ... #Hypertensive #Disorders ... obstetrics #cardiology #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Scarring, atrophy ... permanent alopecia Differential ... ) • Endocrine disorders ... sediment, and elevated ... dysfunction, and mood disorder
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... tenderness • Muscle atrophy ... Muscle weakness + atrophy ... kinase levels are elevated ... #rheumatology #differential
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