15 results
diagnosis lfts treatment cirrhosis liver transaminitis algorithm bacterial biliary differential gastroenterology pbc peritonitis primary sbp spontaneous acute aih ascites autoimmune
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... LFTs #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Phosphatase, ALT ≥ 3x ULN ... ≥ 2x ULN R Value ... = (ALT / ULN ALT ... ) / (ALP / ULN ALP ... Transaminitis #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Severe ALT > 15x ULN ... • Pregnancy - AFLP ... Mild ALT < 5x ULN ... disease US — Normal ... Others #LFTs #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... AST/ALT (5-10x ULN ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... • Near normal ... #differential #Hepatology
Spontaneous Bacterial Peritonitis Clinical • Fever • Chills • Abdominal pain Diagnosis
Diagnosis • PMN ... stain/culture Management ... SBP #Diagnosis #Hepatology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management Ascites PMN > 250/mm3 ? Nosocomial or hospital acquired. Recent
Diagnosis and Management ... Ascites PMN > ... SBP: Medical Management ... response - ↓ PMN ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
upper limit of normal ... Hepatitis (eg Viral) Management ... AND IgG > 2x ULN ... AIH #Diagnosis #Management ... #Hepatology
Ascites - Diagnosis and Management Summary Paracentesis studies: cell count + differential, albumin, protein, culture • Serum-ascites-albumin-gradient
Diagnosis and Management ... source • SBP: PMN ... count (WBC x PMN ... Ascites #Diagnosis #Management ... #Summary #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
• ALT & AST normal ... • Bilirubin - Normal ... obstruction • ALP ... > 1.5 x ULN • ... diagnosis #workup #hepatology
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