9 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... - CBD stone, Biliary ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... Transaminitis #Algorithm #diagnosis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs ... the liver ALP - Biliary ... Value = (ALT / ULN ... #FunctionTest #LFTs ... Transaminitis #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... disease US — Normal ... Duct Stone • Biliary ... • Others #LFTs ... #Differential #Diagnosis
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
2) Lipase > 3x ULN ... Lipase, Ca2+, LFTs ... • Imaging: US (biliary ... , can be normal ... MRCP (necrosis, biliary
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... liver #chemistry #diagnosis ... transaminitis #LFTs
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
upper limit of normal ... , AIH diagnosis ... Hepatitis (eg Viral) Management ... AND IgG > 2x ULN ... #Management #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... No extrahepatic biliary ... • ALP > 1.5 x ULN ... Differential Diagnosis ... #cholangitis #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... Multiple Sclerosis Diagnosis ... lesions) McDonald diagnostic ... #management #neurology
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... if ALP > 1.5x ULN ... and/or abnormal ... #PBC #Primary #Biliary