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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... for 4.6% of new infections ... Droplets that contain bacilli ... Tuberculosis Diagnosis ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... for 4.6% of new infections ... Droplets that contain bacilli ... Tuberculosis Diagnosis ... #Diagnosis #Management
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Abscess: • More bacilli ... with pulmonary TB ... and not direct infection ... #Tuberculosis #diagnosis ... #differential #TB
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of a previously diagnosed ... No specific diagnostic ... (<100), except TB ... TB - Lymphadenitis ... • Leprosy • Bacillus
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
Summary of Infections ... treatment • TB ... meningitis • TB ... (IRIS) (not an infection ... #Indications #infections
Cavitary Lung Disease - Differential Diagnosis and Workup Algorithm
Acute / Subacute:
 • Acute Infections: Lung abscess,
- Differential Diagnosis ... Emboli, Fungal Infection ... ): • Chronic Infections ... : TB, NTB, Fungal ... Lung #Disease #Diagnosis
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... Gram-negative bacilli ... Gram-negative bacilli ... #Transplant #Infections ... #differential #diagnosis
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
- Differential Diagnosis ... CMV, HIV, Toxo, TB ... Melanoma • Axillary: Infection ... , Sjögren's • Infection ... #Differential #Diagnosis
Initiation of ART in HIV patients with Opportunistic Infections
 • Pulmonary TB and CD4 cell count
Opportunistic Infections ... • Pulmonary TB ... • Pulmonary TB ... count >50 • CNS TB ... Opportunistic #Infections
IDSA - Prophylaxis to Prevent First Episode of Opportunistic Disease in HIV-AIDS
 • Pneumocystis pneumonia (PCP)
(TB) • Disseminated ... A and B virus infection ... A virus (HAV) infection ... B virus (HBV) infection ... Opportunistic #Infections