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diagnosis differential neurology management pathophysiology sclerosis acute arthritis benign comparison endocrinology hyperplasia hyperthyroid hyperthyroidism hypothyroid hypothyroidism inflammatory injury joint monoarthritis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... see mechanics hands ... #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... skin thickening Signs ... and Symptoms: ... acro-osteolysis, myositis ... #diagnosis #signs
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... Pattern: Proximal and ... steroids - BWH ... diagnosis #comparison #rheumatology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... and Signs Hypothyroidism ... Dermatopathy Ø Hands ... Amy Chung, MD, MSc ... #Signs #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
: Pathogenesis and ... clumsiness in hands ... rectal reflex. ... pathophysiology #signs ... #symptoms #msk
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
hormones, urine reflux ... , autoimmune response ... bladder stones #BPH ... Pathophysiology #Urology #Signs ... #Symptoms #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... Oligoclonal IgG bands
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... Rheumatologic Disease ... Differential #Diagnosis #MSK ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Gottron sign) ... • Shawl sign • ... • Mechanic's hands ... #rheumatology #
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