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endocrinology diabetes diagnosis pathophysiology ketoacidosis differential management diabetic hypoglycemia algorithm pharmacology causes comparison deficiency diabeticketoacidosis dm2 edka euglycemic hhs hyperglycemic
Insulin and Glucagon Pathophysiology Insulin: • Glucose utilization (Glycolysis) • Glucose storage (Glycogenesis) • Fat synthesis
Insulin and Glucagon ... Pathophysiology Insulin ... uptake in tissues Glucagon ... EricsMedicalLectures/ #Insulin ... #Glucagon #Pathophysiology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Ketoacidosis (DKA ... HHS) Absolute Insulin ... Type I DM: No insulin ... stresses that ↑ insulin ... Polydipsia #dka
Pathophysiology and Effects of Insulin Deficiency #Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
and Euglycemic DKA ... for euglycemic DKA ... • Increased insulin ... and surgery) • Insulin ... Consideration of insulin
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity #DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... Patients with DKA ... Continue insulin ... and subcutaneous insulin ... #DKA #EDKA #Insulin
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... emergencies - HHS = insulin ... restart any home insulin ... look like overlap DKA
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
Starved state” where Glucagon ... Glucagon stimulates ... /Glucagon balance ... DKA is essentially ... the actions of Glucagon
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA) DKA is a result of an absolute or relative insulin
Ketoacidosis (DKA ... ) DKA is a result ... Insulin is the primary ... the absence of insulin ... In DKA, the normal
Hypoglycemia Workup and Differential Diagnosis Workup: • Sulfonylurea Labs • Anti-lnsulin Ab - Insulin Autoimmune Syndrome •
Ab - Insulin Autoimmune ... Serum glucose, Insulin ... hrs - 1mg IV Glucagon ... Sulfonylurea Misuse • Insulin ... Misuse • Insulin
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