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diagnosis differential toxicity pharmacology nephrology algorithm alkalosis management causes table pathophysiology neurology syndrome alcohol aspirin brain hypokalemia radiology salicylate acetaminophen
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
route of APAP metabolism ... formation of the toxic metabolite ... conjugate the toxic metabolite ... routes of liver metabolism ... #Pathophys #Toxicology
Toxic Alcohol Ingestion Alcoholic ketoacidosis - Methanol - Ethylene glycol - Isopropyl Alcohol • Metabolic Acidosis •
Isopropyl Alcohol • Metabolic ... Ingestion #diagnosis #toxicology ... #comparison #table
Ethylene Glycol Toxicity #Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Pathophysiology #Toxicology ... EthyleneGlycol #Metabolism
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic ... LacticAcidosis #Toxicity #Toxicology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Metabolic Alkalosis ... Cl- responsive metabolic ... Post-hypercapneic metabolic ... Cl- resistant metabolic ... diuretic use, Bartter
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
• Salicylates Metabolic ... PLACE” B - Bartter's ... or Cushing’s) Metabolic ... non anion gap metabolic ... - anion gap metabolic
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Cl-: Diuretics, Bartter ... syndrome #Primary #Metabolic
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Low intake • Metabolic ... Renal Losses: • Metabolic ... thiazide diuretics, Bartter
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis ... Cl- responsive metabolic ... Post-hypercapneic metabolic ... Cl- resistant metabolic ... diuretic use, Bartter
Tramadol - Toxicology Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1 This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism
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