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diagnosis rheumatology oncology vasculitis algorithm antinxp2 causes dermatologic dermatomyositis distribution gap globulin gpa hodgkins lupus lymphoma mds myelodysplasia myelodysplastic polyangiitis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
disease or more commonly ... Maculopapular rash ... reticularis Differential ... syndrome • Giant cell ... Polyangiitis #GPA #dermatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
: • Squamous cell ... cell carcinoma ... fungoides (cutaneous T-cell ... : • Sickle Cell ... ulcerative #skinrash #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... permanent alopecia Differential ... Angioimmunoblastic T-cell ... Kidney disease common ... : • Chronic B-cell
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Most common cytopenia ... blood count with differential ... Syndromes #diagnosis #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
rash on the face ... carcinoma • Clear cell ... adenocarcinoma • Non-small-cell ... #diagnosis #management ... dermatology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
adherent scale • Basal ... cell carcinoma ... • Squamous cell ... ; pruritis #dermatology ... #rash #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... CRP GCA (Giant Cell ... Nodosa: • PAN most commonly ... : Erythematous nodules ... , mucositis • Rash
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #hematology #oncology ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Drug Associated (Commonly ... Associated: (± 100 % Commonly ... : erythematous nodules ... mucositis - Rash ... #classification
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... myeloma • Plasma cell ... gastric tumors • Hematology ... Thalassemia, Sickle cell ... #diagnosis #hematology
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