8 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... thrombocytopenia, Autoimmune Hemolytic ... #Allergic #Reactions ... #Types #Classification
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Hours to Days (Hemolytic ... reactions #Types #Classification ... #Allergy #Diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... cellular antigen, leading ... types or during hemolytic ... Hypersensitivity #Types #Classification
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... Bartonella, Babesia ... udaygulati #Hemolytic ... Diagnosis #causes #classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... cell antigens, leading ... transfusion reaction, Haemolytic ... reactions #types #allergy ... #table #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... to an allergic ... antigen-surface complex, leading ... immune reaction, leading ... #Types #Classification
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... recipient antibodies leading ... to hemolysis & ... • Allergic reaction ... Injury (TRALI): Leading
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
recipient antibodies leading ... to hemolysis & ... Hemolysis on labs ... - Allergic ... Injury (TRALI): Leading