22 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... Sickled red cells ... disease Bite cells ... Peripheral #Blood #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
Dacrocytes (tear drop cells ... metaplasia, pernicious anemia ... some hemolytic anemias ... BloodSmear #Blood #Smear
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Peripheral blood smear ... History • Bite cells ... Deficiency • Sickle cells ... → Sickle Cell anemia
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... polychromatophilic cells ... arrow) Peripheral smear ... Hematology #Pathology #Smear
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Codocytes (Target cells ... ) - Two target cells ... Target cells are ... with hemolytic anemias ... BloodSmear #Blood #Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Pernicious Anemia ... Macrocytosis, Target Cells ... #Macrocytic #Anemia
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
schizocytes, these cells ... shapes of red cells ... seen in hemolytic anemias ... microangiopathic hemolytic anemia ... BloodSmear #Blood #Smear
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Marrow (Toxic injury ... number of CD34+ cells ... number of CD34+ cells