31 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... Reticulocytes, MCV ... , MCH, MCHC, Serum ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... peripheral blood smear ... changes), high MCV ... patients if the cause ... dysplasia on the smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Corpuscular Volume (MCV ... Normal Blood Smear ... Macrocytosis, Target Cells ... Diagnosis #Algorithm #Causes
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... 🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Peripheral blood smear ... History • Bite cells ... Deficiency • Sickle cells ... Diagnosis #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Overview: ALL, CML ... peripheral blood smear ... involvement CML ... -> AML: Blast crises ... • Peripheral smear
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
In this case, arrows ... point to helmet cells ... cell, 2 blister cells ... acanthocyte), and 2 burr cells ... BloodSmear #Blood #Smear
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
the red blood cells ... than 150,000 per mcL ... than 4000 per ml ... These causes could ... /mean MCV) × 100