51 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... peripheral-blood smear ... revealed 25% plasma cells ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... 𝐩𝐫𝐨𝐥𝐲𝐦𝐩𝐡𝐨𝐜𝐲𝐭𝐞𝐬: small to medium ... Prolymphocytes #Smear
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Rapidly rising blast cells ... -> AML: Blast crises ... : Granulocytic cells ... • Peripheral smear
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... Hematology #Clinical #Smear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... anemia Sickled red cells ... disease Bite cells ... Alcohol abuse, Heavy metal ... Peripheral #Blood #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... Hematology #Pathology #Smear
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... Chronic myelogenous leukemia ... Polycythemia vera Acute Leukemia ... pancytopenia, blast cells ... Diagnosis #Algorithm #Causes
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Leukemoid reaction ... Leukemias or myeloproliferative ... Leukemoid Reaction ... D/D leukemia: increases ... the underlying cause
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Skin: - CLL cells ... • Peripheral smear ... : Smudge cells or ... basket cells can