23 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... anemia Sickled red cells ... disease Bite cells ... Alcohol abuse, Heavy metal ... Peripheral #Blood #Smear
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... 𝐩𝐫𝐨𝐥𝐲𝐦𝐩𝐡𝐨𝐜𝐲𝐭𝐞𝐬: small to medium ... size lymphoid cells ... Prolymphocytes #Smear
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia - Differential ... Peripheral blood smear ... History • Bite cells ... Deficiency • Sickle cells ... Hemolytic #Anemia #Differential
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Normal Blood Smear ... Macrocytosis, Target Cells ... #elevatedMCV #Differential
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
adsorption onto cancer cells ... disorders • Shear ... treatment #hematology #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
incidentally during medical ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... Disorders #Algorithm #Differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... Peripheral Smear ... Exposure to heavy metal ... blood count with differential ... Peripheral blood smear
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytes • Median ... • Peripheral smear ... lymphocytes, smudge cells