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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Vaughan Williams Classification ... this class are beta ... blockers.⠀ Class ... III agents - Potassium ... #Medications #Classification
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... duration CLASS 2 - Beta ... repolarization CLASS 3 - Potassium ... alpha & beta adrenergic ... #Pharmacology #Classification
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Angiotensinogen • Beta ... : C3 and C4, Beta ... Proteins #Subtypes #algorithm ... #classification ... #Types #hematology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... duration CLASS 2 - Beta ... repolarization CLASS 3 - Potassium ... alpha & beta adrenergic ... #Pharmacology #Classification
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
obstruction _ pHA type ... I, type II - ... diseases _ pHA type ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... adrenergic receptor blockers ... Failure • SLE • Type
Summary of Heart Blocks
1st Degree Heart Block:
 • Prolonged PR >200ms (5 small squares).
 • Narrow
Summary of Heart Blocks ... before dropped beat ... after dropped beat ... #HeartBlocks #Types ... #Classification
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... adrenergic receptor blockers ... Failure • SLE • Type
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Hyperkalemia Treatment Algorithm ... bradycardia, AV blocks ... Combo of insulin + beta-agonist ... glucose <100 • Beta-agonist ... treatment Remove potassium
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
are listed as Type ... source of energy, conversion ... Nonhypoxic • Type ... medications - Beta ... #typeb #classification