26 results
Glucagon: Bypassing β-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
β-Blockade Glucagon pathophysiology ... applications in anaphylaxis ... and beta-blocker ... #Pharmacology #Pathophysiology ... BetaBlockade #Overdose #Anaphylaxis
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Pharmaceutical Management ... Thyroid Storm Beta-Blockers ... peripheral conversion ... • Decreases conversion ... #ThyroidStorm #Management
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
Diagnostic and Management ... Algorithm CONSIDER ... Hypothyroidism - TOX: beta-blockers ... LIFE THREATENING CAUSES ... TREATMENT - Drugs (beta-blockers
Management of acute beta blocker/calcium channel blocker overdose

#Management #Toxicology #BetaBlocker #CCB #CalciumChannelBlocker #Overdose #Toxicity #Algorithm
Management of acute ... beta blocker/calcium ... channel blocker ... overdose #Management ... Overdose #Toxicity #Algorithm
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
, beta1 > beta2) ... > beta2 / alpha1 ... • 1st agent in anaphylaxis ... cAMP/cGMP • Causes ... Pharmacology #Summary #management
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... : • MOA: Block ... 2 - Beta Blockers ... alpha & beta adrenergic ... #pathophysiology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in ... Cirrhosis • Pathophysiology ... Cirrhosis #hepatology #management
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... Beta-blockers and ... Ventolin inhaler #Anaphylaxis ... #Treatments #Management ... #pathophysiology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Amyl nitrite - causes ... thiosulfate enhances conversion ... Toxicity #Toxicology #Pathophysiology ... #Management #Treatment
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: • MOA: Block ... 2 - Beta Blockers ... : • MOA: Block ... alpha & beta adrenergic ... #pathophysiology