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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Antiarrhythmic Medications ... class are beta ... blockers.⠀ Class ... EricsMedicalLectures/ #Antiarrhythmic ... Summary #Table #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... duration CLASS 2 - Beta ... alpha & beta adrenergic ... accpcardprn #Antiarrhythmics ... Vaughan #Williams #Pharmacology
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
Class I Antiarrhythmics ... and their Key Pharmacologic ... Fries Please") Block ... ClassI #Class1 #Antiarrhythmics ... Agents #Cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... duration CLASS 2 - Beta ... @accpcardprn #Antiarrhythmics ... #Pharmacology #
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
weak inotropic agent ... cardioversion, antiarrhythmics ... Initiation of beta-blocker ... failure - Any beta-blocker ... #HeartFailure #Cardiology
Treatment of Stable Wide-Complex Tachycardia
Regular
 • If ventricular tachycardia or uncertain rhythm:
    -
Avoid AV nodal agents ... (e.g., diltiazem ... or B-blockers) ... - Consider antiarrhythmics ... Treatment #management #cardiology
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
- treat with beta-agonist ... 60 (1) Sinus bradycardia ... #EKG #diagnosis ... #electrocardiogram ... #cardiology #differential
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
increased bleed risk Beta-Blockers ... Decreases effects of beta-blockers ... arrhythmias Class I Antiarrhythmic ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Approach to ECGs
Check
 - Age, gender, name
 - 25mm/s; 10mm/mV
 - 1mm = 40ms; 0.1 mV
Rate
) - HiPR: AV block ... antihistamines, antiarhythmics ... #EKG #diagnosis ... #electrocardiogram ... #cardiology #interpretation