38 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Clinical Presentation ... younger pts) Differential ... #anemia #hematology ... #diagnosis
Patterns of Diseases on MRI FLAIR - Differential Diagnosis
ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
on MRI FLAIR - ... Differential Diagnosis ... #MRI #Differential ... #Diagnosis #neuroradiology ... #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold agglutinins ... inclusions - If infection ... #workup #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Internal (RBC) - Infections ... - Unconjugated Bilirubin ... #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . primary cold agglutin ... spherocytosis) • Infections ... Extravascular #Causes #differential ... #diagnosis #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... - **MSK rads ... Differential diagnosis ... diffuse chondral disease ... #diagnosis #msk
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
Sporotrichiosis Infection ... wax and wane; diagnosis ... biopsy preferred Differential ... Diseases Fellowship ... #clinical #photo
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... • MRI is more sensitive ... tibial tuberosity Differential ... #mri #clinical ... #msk
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... Diagnosis: Vasculitis ... • Fungal infections ... #rash #diagnosis
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
(HADD) - MSK Radiology ... • MRI shows globular ... Differential diagnosis ... #clinical #mri ... #diagnosis #msk