70 results
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Metabolism of Bilirubin ... → Unconjugated Bilirubin ... "indirect bilirubin ... interchangeably for routine clinical ... pathophysiology #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... fold elevation, Bilirubin ... fold elevation, Bilirubin ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... of Alcoholic Hepatitis ... • Serum total bilirubin ... Possible ischemic hepatitis ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... - Serum total bilirubin ... Possible ischemic hepatitis ... #Diagnosis #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... week • Direct bilirubin ... Chronic viral hepatitis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
week • Direct bilirubin ... Chronic viral hepatitis ... Elevation: • Bilirubin ... liver #injury #hepatitis ... diagnosis #algorithm #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
as jaundice on clinical ... birth with serum bilirubin ... associated with bilirubin ... in conjugated bilirubin ... #hepatology #diagnosis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2, bilirubin ... liver failure #HepatitisB ... Indications #management #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... function: INR, bilirubin ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Stenosing Flexor Tenosynovitis or Trigger Finger on Physical Exam

Dr. Sergi Barrera @dr.sergibarrera

#TriggerFinger #Trigger #Finger #Stenosing #flexor
tenosynovitis #msk ... #clinical #physicalexam ... #orthopedics #rheumatology