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diagnosis differential clinical hepatology management algorithm causes pocus ultrasound treatment hematology pathophysiology radiology hepatic gastroenterology infectiousdiseases pharmacology photo physicalexam table
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... week • Direct bilirubin ... Chronic viral hepatitis ... Elevation: • Bilirubin
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune: Autoimmune hepatitis ... week • Direct bilirubin ... Chronic viral hepatitis ... Elevation: • Bilirubin ... #injury #hepatitis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... fold elevation, Bilirubin ... fold elevation, Bilirubin ... but variable ++, Bilirubin ... hepatology #obstetrics #hepatitis
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
of Autoimmune Hepatitis ... - Serum total bilirubin ... Possible ischemic hepatitis ... ) or metabolic liver ... Possible drug-induced liver
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
diagnosis of Alcoholic Hepatitis ... • Serum total bilirubin ... Possible ischemic hepatitis ... ) or metabolic liver ... Possible drug-induced liver
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... infection with severe liver ... injury (INR > 2, bilirubin ... mg/dL) or acute liver ... failure #HepatitisB
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
function: INR, bilirubin ... Cirrhosis/acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... slightly elevated • Bilirubin ... or higher • Liver ... Diagnosis: • Viral hepatitis
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... • Conjugated Bilirubin ... • Unconjugated Bilirubin ... LouLectures #Bilirubin ... Pathophysiology #hepatology #Liver
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Liver Function Tests ... transpeptidase (GGT) - Bilirubin ... Prothrombin #Liver
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