12 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Rivaroxaban - Apixaban ... Target - Prodrug - Bioavailability ... #Pharmacology #NOAC ... #comparison #table ... #rivaroxaban #apixaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... Xa inhibitors - Apixaban ... #pharmacology #medications ... #doac #comparison ... #table #management
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Sheet: Warfarin, Apixaban ... Anticoagulant #DOAC ... #Management #Table
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... Quick tip: apixaban ... #Warfarin #DOAC ... #Pharmacology #Table
Isolated Neutropenia - Differential Diagnosis Algorithm
Chronic (>3 months):
 • Extrinsic: Vitamins
 • Intrinsic: Congenital, Inflammatory
Transient:
 •
Differential Diagnosis Algorithm ... Non-infectious • Medications ... Noah Rosenberg @ ... Differential #Diagnosis #Algorithm
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... content/133/4/291 #DOAC ... #Interactions #Table
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... #management #algorithm ... pharmacology #treatment #medications ... #table #pharmacotherapy
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
determine timing of DOAC ... per treatment table ... inhibitor) • Apixaban ... postoperative #DOAC
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Opioid Stewardship Algorithm ... Non-Opioid Analgesia (NOA ... Medication Assisted ... #Stewardship #Algorithm
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
- Allergies to medications ... functional status - Able ... metabolic equivalent able ... event, follow ACC algorithm ... Stable patients