26 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
twitter.com/AmyChung #AntiCoagulation ... #Cascade #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... DOAC, Parenteral anticoagulant ... #DOACs #anticoagulation ... #Switching #hematology ... #pharmacology
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... CHADS2-VASc and HAS-BLED ... #Diagnosis #Hematology ... #Risk #Stroke #Bleed ... #Anticoagulation
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Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Dosing #Oral #Anticoagulant ... #Anticoagulation ... #Loading #DVT #Pharmacology ... #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... to assess for anticoagulant ... and procedural bleeding ... with a very low bleeding ... Management #Treatment #pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... - Pathophysiology ... Anticoagulation ... warfarin) for chronic anticoagulation ... #Pharmacology #Pathophysiology
Anticoagulation Review. There are other bleeding risk assessment tools, but HAS-BLED is more commonly used. HTN
Anticoagulation ... tools, but HAS-BLED ... Bleeding includes ... Purposes Only* #Anticoagulation ... #Anticoagulant
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
- HAS-BLED (atrial ... clinical benefit of anticoagulation ... of withholding anticoagulation ... #Calculators #Anticoagulation ... #Factors #Hematology
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
Choice of anticoagulant ... history of Gl bleed ... Pregnancy - LMWH #anticoagulant ... decisionaid #vte #anticoagulation ... #pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal