Choice of anticoagulant for treatment of pulmonary embolism
• Malignancy - LMWH
• To avoid parenteral therapy - Rivaroxaban; apixaban
• Once a day oral therapy - Rivaroxaban; edoxaban; VKA
• Hepatic involvement with coagulopathy - LMWH
• Renal involvement with creatinine clearance <30 mL/min - VKA
• Dyspepsia or history of Gl bleed - VKA, apixaban
• Thrombolyzed patients - UFH
• Need of reversal agent - VKA, UFH
• Pregnancy - LMWH
#anticoagulant #selection #decisionaid #vte #anticoagulation #pharmacology