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diagnosis differential management algorithm blood pancytopenia reactions b12 cobalamin extravascular folate folicacid hemolysis intravascular mds mentzerindex myelodysplasia myelodysplastic neutropenia oncology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • Alloimmune delayed ... • PK deficiency ... immune-complex hemolytic anemia ... #Hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate Deficiency ... have hemolytic anemia ... folate that can cause ... differential #diagnosis #hematology ... #nutrition
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... some symptoms related ... RBC are produced ... Pancytopenia is a hematologic ... These causes could
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... derived from animal products ... • Common Causes ... pain, diarrhea related ... diagnosis #management #nutrition
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
LDH, etc) - Delayed ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
↑LDH, etc) • Delayed ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Platelet Disorders • Nutritional ... or folic acid deficiency ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology
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