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diagnosis differential management rheumatology disease pseudogout abnormal calcium chondrocalcinosis color ddxof deposition dermatology enzymes gout hemeonc hemophagocytic hepatology hlh inflammatory
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... instability - New-onset ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... characterized by sudden onset ... • Nocturnal onset ... #Gout #Comparison ... #rheumatology #
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... joint (sudden onset ... #Disease #Signs ... #Symptoms #Pathophysiology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Dermatomyositis • Onset ... heliotrope, shawl sign ... Polymyositis • Onset ... differential #diagnosis #comparison ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... intracellular contents ... diagnosis #management #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... clinical symptoms/signs ... elevation and clinical context ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... ) Pathophysiology ... calcium to form CPP ... characterized by sudden onset ... Deposition #Disease #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
- Onset: Usually ... Presentation • Common Signs ... Pathophysiology ... Diagnosis #Management #Hematology
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