14 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Differential Diagnosis Algorithm ... Signs of anemia ... Membrane defects, Enzyme ... Differential #Diagnosis #Algorithm ... #hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... instability - New-onset ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
of the NTPPPH enzyme ... and/or x-ray - CPPD ... joint (sudden onset ... #Disease #Signs ... #Symptoms #Pathophysiology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... clinical symptoms/signs ... the magnitude of enzyme ... elevation and clinical context ... #Hepatology #Liver
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... characterized by sudden onset ... • Nocturnal onset ... Gout #Comparison #rheumatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... ALP: - Enzymes ... -> US/Surgical consult ... Differential #Diagnosis #Algorithm ... #hepatology
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Pathophysiology: ... In the context of ... of pancreatic enzymes ... Diagnosis and Context ... days after the onset
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... intracellular contents ... diagnosis #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... nephrocalcinosis • CPPD ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... ) Pathophysiology ... calcium to form CPP ... characterized by sudden onset ... Deposition #Disease #Rheumatology