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diagnosis differential intravascular management anemia blood dermatology dic disseminated extravascular hemolysis nonpalpable palpable product purpura reactions rheumatology transfusions treatment
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... HUS) • Other: Transfusion ... Extravascular #Causes ... differential #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... DIC/TTP/HUS - Hemolytic ... Fragility: • Decreased ... Differential #Diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Treat primary cause ... hydration • RBC transfusion ... #diagnosis #causes ... treatment #management #hematology
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