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diagnosis hepatology hematology lfts liver transaminitis apml bandemia chemistry differentiation elevated enzymes hepatitis injury interpretation liverfunctiontests management neutrophil oncology polycythemia
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... LFTs #Elevated #Abnormal ... Transaminitis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... function may be abnormal ... muscle, kidneys • LDH ... #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... - If both are normal ... • Near normal ... muscle, Kidneys • LDH ... chemistry #diagnosis #differential
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
) Differential ... appreciate the value ... science/article/abs ... bacteremia • Abnormal ... #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... body mass index; FBC ... normalised ratio; LDH ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... 500 mg QD until normal ... WBC • Continue
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Diagnosis Algorithm ... that a one-off value ... else is driving RBC ... MPNs (MPL, CALR, also
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