20 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... allele of RB1 tumor ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... Signs/Symptoms: ... between bone and tumor ... around the bone tumor ... BoneTumors #Malignant #Radiology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... hyperplasia and tumors ... , Adrenal rest tumor ... #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperreflexia - Tremor ... Hyperthyroidism #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
GHRH hypothalamic tumors ... neuroendocrine tumors ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
the pituitary tumor ... ) as secreting tumors ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Diagram of different types of bone tumors that can occur around the knee on XRay -
types of bone tumors ... • Giant cell tumor ... blade of grass sign ... Diagnosis #Bony #Differential ... #Radiology #XRay
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
• Weakness or tremors ... TSH-producing pituitary tumors ... causes #diagnosis #differential ... #endocrinology ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
types of bone tumors ... • Giant cell tumor ... blade of grass sign ... Lesions #Bony #Differential ... #Diagnosis #Radiology