8607 results
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rheumatic pain Clinical ... • Bone and joint ... Diagnosis: • A clinical ... and lower jaw Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... Assessment • Clinical ... /ml, ↑ LDH • Bone ... Unknown cause Treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Aplastic Anemia Clinical ... • Suggested by bone ... hypoplasia/fatty bone ... aplastic anemia Treatment
Syphilitic gummas in Tertiary syphilis
Tertiary syphilitic gummas may mimic basal cell carcinoma. The gummatous tumors are
Without treatment ... vessels, liver, bones ... Tertiary #syphilis #clinical
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Management Summary Clinical ... disease Imaging and Treatment ... Bone scan is indicated ... patients with bone
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... CD163 staining of bone ... is found in the bone ... Treatment: • Corticosteroids
Interstitial keratitis in Tertiary Syphilis

Interstitial keratitis, which is an inflammation of the cornea’s connective tissue elements,
Without treatment ... vessels, liver, bones ... Tertiary #syphilis #clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Hemophagocytosis in bone ... • Bicytopenia Treatment ... diagnosis #management #treatment
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma of bone ... • Occur in bone ... ) or outside bone ... plasmacytoma) Clinical ... marrow Treatment
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
APL) following a bone ... hospitalization and treatment ... #Clinical #Path