150 results
Pancytopenia - Differential Algorithm / Schema

- Bone Marrow Failure
- Bone Marrow Infiltration
- Sequestration / Destruction

#Pancytopenia #Differential
/ Schema - Bone ... Marrow Failure - Bone ... Algorithm #Schema #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
production: • Bone ... suppression • Bone ... marrow failure • Bone ... Diagnosis #Algorithm #hematology
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... Peri-articular osteopenia (bones ... Radiology #Clinical #Pathophysiology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... Hematogenous spread as source ... BrighamChiefs #Bone ... diagnosis #causes #hematology
Nephron Pathophysiology Study Guide 

- Proximal Tubule
- Loop of Henle
- Distal Tubule
- Collecting Duct

The Kidney Zone

#Nephron
Nephron Pathophysiology ... The Kidney Zone ... #Nephron #Nephrology ... #Pathophysiology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
absorption ↑ bone ... Hypophosphatemia: ↑ bone ... Calcium #Phosphorus #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... : Inhibitor of bone ... formation causing poor bone ... respiratory failure • Neurologic ... Skeletal: - Bone
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Renal disease - Bone ... DDX of Hepatic source ... Diagnosis #Algorithm #hepatology
Cushing's Reflex - Pathophysiology
HYPERTENSION with a reflex BRADYCARDIA
 → ↑ ICP 
 → ↓ CBF
 →
Cushing's Reflex - Pathophysiology ... → ↑ Vasomotor tone ... Cushings #Reflex #Pathophysiology ... #neurology #nsg
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology