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management treatment diagnosis hivaids idsa opportunistic prevention antibiotics differential disease neurology table workup algorithm anesthesiology chagas checklist comparison diabetes dm2
Tigecycline (IV) - Antibiotics Class Overview Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic). Only
Spectrum: Broad ... intraabdominal infections ... skin/soft tissue infections ... #Pharmacology #Antibiotics
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia Signs of severe toxicity: • Sudden alteration in
for Crises in Anaesthesia ... bradycardia, conduction blocks ... after an initial injection ... for crises in anaesthesia ... Anesthesiology #Anesthesia
Modified penicillin binding proteins as mechanism of resistance to antibiotics. Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
- Vancomycin blocks ... more antibiotic (e.g ... amox for an ear infection ... cephalosporin (e.g ... Proteins #AMR #PBP #pharmacology
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Weight loss (~2-3kg ... hypovolemia) • GU infections ... (e.g. ... SGLT2 #Inhibitors #Pharmacology
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
for Crises in Anaesthesia ... ≥ 4mmol.l-1 if infection ... cultures if possible (eg ... for crises in anaesthesia ... Anesthesiology #Anesthesia
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Non-specific (infections ... vs non-infectious ... host response to infection ... fluids (30 mL/kg ... 1st 3 hours) • Broad-spectrum
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
- Following 3 broad ... Calcium oxalate Infectious ... Acute or chronic infections ... joint trauma (e.g ... derangements (e.g
IDSA Recommendations for Treating Visceral and Cutaneous Leishmaniasis in HIV-AIDS Treating Visceral Leishmaniasis - Preferred Therapy: •
., 4 mg/kg on days ... dose of 20–60 mg/kg ... ., 4 mg/kg on days ... opportunistic #infections ... #HIVAIDS #pharmacology
Emergency Treatment Algorithm for Convulsive Status Epilepticus 1. ABCDEFG (ABC's and Don't Ever Forget the Glucose) 2. Airway:
Lorazepam 0.1 mg/kg ... Phenytoin 20 mg/kg ... Valproate 40 mg/kg ... Consider consulting anesthesia ... Management #Neurology #Pharmacology
Coverage of common antibiotics used in the hospital For empiric coverage, first define the type of infection,
define the type of infection ... prior resistance. e.g ... #antibiogram #pharmacology
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