18 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Action #nephrology #pharmacology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... parenteral agents (e.g ... anticoagulant (e.g ... anticoagulant (e.g ... #Pharmacology #Pathophysiology
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
Lorazepam 0.1 mg/kg ... Phenytoin 20 mg/kg ... Valproate 40 mg/kg ... Consider consulting anesthesia ... Management #Neurology #Pharmacology
Practice Guidelines for Preoperative Fasting

Infographic by Dr. Jesse Burk-Rafel
@jbrafel

> 8 hours - Heavy foods (fried/fatty) and
- Light meal (e.g ... clear liquids (e.g ... and the Use Of pharmacologic ... Fasting #Guidelines #Anesthesia
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
anticoagulant drugs (e.g ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
amnesia • hypnosis • anesthesia ... amnesia • hypnosis • anesthesia ... Antagonists: - Blocks ... #medications #pharmacology
Tweetorial - How do calcium channel blocks (e.g., amlodipine) cause edema? 

By Dr. Tony Breu @tony_breu

#CCB
calcium channel blocks ... (e.g., amlodipine ... CalciumChannelBlockers #Tweetorial #Pathophysiology ... #Pharmacology
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
- Vancomycin blocks ... more antibiotic (e.g ... cephalosporin (e.g ... vancomycin to CTX (e.g ... Proteins #AMR #PBP #pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... - When digoxin blocks ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology