9 results
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... #Diagnosis #Management ... FebrileSeizure #Fever ... #Workup #Simple ... #Complex
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... Antigen-antibody complexes ... Complement activation ... #Classification ... Pathophysiology #Allergy #Diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Anaphylaxis, Hay fever ... Antigen-antibody complex ... Antigen-antibody complexes ... they activate complement ... allergy #table #classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
peanuts), Hay fever ... conjunctivitis Type ... Antigen-Ab immune complexes ... #Classification ... #Diagnosis #Definitions
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... Labs/Diagnosis: ... • Low serum C4 complement ... Cryoglobulins #diagnosis ... #types #classification
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Red Flags: • Fever ... deficiency Work ... Up: • Complete
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... Differential Diagnosis ... Kikuchi disease • Type-I
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Workup: • Kidney ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types ... #Significance #Diagnosis