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diagnosis hypersensitivity reactions rheumatology glomerular management nephrology nephrotic table testing workup allergic antibiotics c4 comparison cryoglobulinemia cryoglobulins definitions differential disease
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 ... ↓↓ • MCGN type ... • Cryo C3 ↓ C4 ↓ ... ThePeanutKidney #Complement
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... glomerulonephritis, Serum ... sickness Type ... #Types #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type ... (Anaphylaxis) Type ... Complex-Mediated, 1-3 Weeks (Serum ... #Classification ... #Allergy #Diagnosis
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Subtypes of Serum ... Angiotensinogen • Beta: C3 ... Proteins #Subtypes #algorithm ... #classification ... #Types #hematology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... antigens, leading to complement ... they activate complement ... #allergy #table ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
are Igs in the serum ... the presence of serum ... level • Low serum ... C4 complement level ... #classification
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
Maculopapular rash (mild type ... Use carbapenem Type ... Type II-IV HSR ... - Serum sickness ... #Prescription #algorithm
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
expensive Serum ... Serum or urine for ... C3, C4 - Test for ... or alternative complement ... cryoglobulinemias (types
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
expensive 2) Serum ... microangiopathy. 5) C3 ... or alternative complement ... Serum or urine for ... cryoglobulinemias (types
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