6 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... antigens, leading to complement ... they activate complement ... allergy #table #classification
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... NETs), cytokines, complement ... COMMON CAUSES + ... • Symptoms: Fever