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diagnosis classification comparison differential hypersensitivity reactions rheumatology types c1inh causes deficiency diffuse druginduced esterase glomerulonephritis hematology inhibitor lad lymphadenopathy management
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... , and systemic lupus ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... they activate complement ... glomerulonephritis, Systemic lupus ... reactions #types #allergy ... #table #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... 90% - Low complement ... 80% - Low complement ... sle #comparison #table
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... • Systemic Lupus ... • Acne • Allergy ... Differential #Diagnosis #Algorithm
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... Deficiency Testing Algorithm ... ARUPLabs #C1INH #Complement ... Deficiency #Testing #Algorithm ... #allergy #diagnosis
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