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diagnosis differential rheumatology types allergy cardiology comparison cryoglobulinemia cryoglobulins dermatology erythematosus gammopathy glomerulonephritis hemoptysis hypersensitivity massive mgrs monoclonal pericarditis petechiae
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Causes of Hemoptysis ... Differential Diagnosis Algorithm ... • Pulmonary Vasculitis ... • Lupus Erythematosus ... #Causes #Pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... (e.g. systemic lupus ... diagnosis #types #classification
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... Differential Diagnosis Algorithm ... arthritis • Systemic lupus ... spondyloarthropathies • Vasculitis ... #Causes #Cardiology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... RNP antibodies, Complement
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... #Causes #dermatology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus ... allergy #table #classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... Clinical Clues: ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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