11 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Penicillin-induced drug reaction ... • Ex: Systemic Lupus ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... Allergen-specific lgE causes ... they activate complement ... glomerulonephritis, Systemic lupus ... allergy #table #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... Complement activation ... , and systemic lupus ... #Types #Classification ... Allergy #Diagnosis #Reactions
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... Differential Diagnosis Algorithm ... ) reaction to inhaled ... Arthritis, Systemic Lupus ... Diseases #ILD #Causes
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... hemolytic transfusion reactions ... #Hemolysis #Classification ... #Algorithm
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Differential Diagnosis Algorithm ... Bullous impetigo - Reaction ... Bullous systemic lupus ... diabeticorum) - Reaction ... #causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... cell surfaces causes ... exposure to allergen causes ... #Hypersensitivity ... #Types #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... (e.g. systemic lupus ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... such as systemic lupus ... disease, drug reactions ... against MPO • Complement ... #rheumatology #classification