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diagnosis rheumatology types allergy reactions vasculitis erythematosus sle systemic table allergic comparison criteria cryoglobulinemia cryoglobulins definitions differential eularacr pathophysiology size
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... Complement activation ... , and systemic lupus ... #Types #Classification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity ... Summary Type I Hypersensitivity ... Disease Type III Hypersensitivity ... • Ex: Systemic Lupus ... Reactions #Types #Classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... Acute cutaneous lupus ... anticoagulant • Complement ... #EULARACR #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
table of types of hypersensitivity ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus ... allergy #table #classification
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... vasculitis - hypersensitivity ... - systemic lupus ... dermatomyositis #Size #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... vasculitis • Hypersensitivity ... (e.g. systemic lupus ... diagnosis #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... Acute cutaneous lupus ... RNP antibodies, Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... #rheumatology #classification
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