6 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Effect of Selected Diseases ... on Complement Levels ... MCGN type 1 C3 ↓ ... C4 ↓↓ • Cryo ... #Levels #C3 #C4
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... rheumatoid factor level ... • Low serum C4 ... complement level ... #classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
monitoring low-level ... C3, C4 - Test for ... or alternative complement ... cryoglobulinemias (types ... glomerular #testing #workup
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Classification: ... • Type-I Interferonopathies ... levels (C3 and ... activity • C3 C4
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
monitoring low-level ... microangiopathy. 5) C3, C4 ... or alternative complement ... cryoglobulinemias (types ... #workup #diagnosis
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
should use this algorithm ... select reference level ... The type of specimen ... depending upon disease ... See table below