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diagnosis differential rheumatology comparison lupus types allergy causes dermatology erythematosus reactions systemic clinicopathology compared criteria cryoglobulinemia cryoglobulins diffuse disease druginduced
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... • Low serum C4 complement ... • Hypersensitivity ... erythematosus (SLE ... diagnosis #types #classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... types of hypersensitivity ... Allergen-specific lgE causes ... types #allergy #table ... #classification
Causes of Diffuse Lung Disease. Collagen vascular - Scleroderma - Rheumatoid arthritis -
Causes of Diffuse ... Dermatomyositis - SLE ... inhalation - Hypersensitivity ... - Toxic gas Vasculitides ... #Differential #Causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... : • Hypersensitivity ... • Ig A vasculitis ... Associated - SLE ... HCV, HBV Not Vasculitis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... Complement activation ... #Types #Classification ... Diagnosis #Reactions #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... tract, and often causes ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... spondyloarthropathies, vasculitides ... See below for table ... helpful paper complements ... #Differential #Table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... 90% - Low complement ... Positive in 60-80% of cases ... 80% - Low complement ... #comparison #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... anticoagulant • Complement ... #Criteria #SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... RNP antibodies, Complement
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