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diagnosis differential nephrology management workup anemia glomerulonephritis hematology hemolytic hepatology nephrotic pulmonary renal rheumatology treatment abnormal agglutinin aki antivirals brincidofovir
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial ... testing for patients ... disease 24- ... or alternative complement ... for ANCA-related vasculitis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial ... testing for patients ... or alternative complement ... for ANCA-related vasculitis ... #glomerular #disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... : - Kidneys: glomerular ... (Granulomatous disease ... atherosclerotic disease ... against MPO • Complement
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis ... sclerosis • Anti-Glomerular ... testing: anti-ANCA
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... present on repeat testing ... including overnight testing ... • Drugs Glomerular ... Minimal change disease
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA ... differential #diagnosis #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell disease ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Disease ... Cryoglobulins (Vasculitic ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... figure details the initial ... yellow indicate the initial ... decision for repeat testing ... LFTs #Abnormal #Algorithm
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