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diagnosis rheumatology differential large cutaneous dermatology size vesselsize anca clinical cryofibrinogenemia cryoglobulins ddxof dermpath erythematosus gammopathy glomerulonephritis hematology im lesions
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... #Small #Medium ... #Vessel #Size #Classification ... #Differential #Algorithm
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
, medium vessel ... small vessel vasculitis ... Medium vessel vasculitis ... Small vessel vasculitis ... #Classification
Break down Vasculitis based on vessel size #Diagnosis #Rheumatology #Differential #Vasculitis #VesselSize #Small #Medium #Large #Classification
Break down Vasculitis ... #Differential #Vasculitis ... #VesselSize #Small ... #Medium #Large ... #Classification
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Findings: • Small ... Urticaria • Medium ... ulceration Small ... Urticarial/LCV) - Cryoglobulinemic ... elevatum diutinum Medium
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... • Low serum C4 complement ... • Cutaneous small-vessel ... vasculitis • ... diagnosis #types #classification
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
semiology of Cutaneous Vasculitis ... involvement of small ... wall vessels (medium-sized ... hemopathies (4%) • Cryoglobulinemia ... vasculitis (3%)
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... + MPO-ANCA MEDIUM ... pain, infarct • Small ... against MPO • Complement ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Lupus Nephritis, Cryoglobulinemia ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... Vasculitis Vasculitis ... of medium vessels ... of small vessels ... dermatomyositis #Size #Classification
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
, fibronectin, small ... malignancies, vasculitis ... , sepsis or cryoglobulinemia ... : Occlusion of small ... to medium-sized
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