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diagnosis differential hematology vasculitis algorithm autoimmune biliary chronic cirrhosis classification cll comparison dermatology disorders druginduced eosinophil eosinophilia hepatology leukemia lupus
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
proximally to arms ... and Symptoms: ... primary biliary cholangitis ... Scleroderma #SSc #rheumatology ... #workup
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... are asthma, allergy ... organ-specific signs ... or symptoms (eg ... , skin or esophageal
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Examination: • Skin ... #diagnosis #workup
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... #dermatology #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... • Immunologic Workup ... sle #comparison #table ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... loss, arthralgia, arm ... , mucositis • Rash ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... just beneath the skin ... that are caused ... #oncology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... : • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused
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